Quaternary ammonium N,N-dichloroamines as topical, antimicrobial agents.

N , N , N - triethyl ammonium L - Phenylalanine esters as potential antimicrobial agents

Quaternary ammonium compounds are an important class of molecules with wide variety of applications, mainly in the antimicrobial field. Quaternary ammonium compounds have the ability to bind with the anionic moiety of phospholipids of the bacterial membrane, disrupting the cell membrane of the microorganisms. However, classical quaternary ammonium salts can have adverse effects on the environme...

Bactericidal and sporicidal activity of a quaternary ammonium resin-triiodide complex.

Tests to determine the potential use of a quaternary ammonium resin-triiodide complex as a sterilizing agent showed that it was an ineffective sporicide and that bactericidal activity was impaired by complex milieu.

Synthesis and antimicrobial activity of quaternary ammonium silane coupling agents.

Fourteen novel silane coupling agents with a quaternary ammonium group introduced into the molecule, [CH(2)=CHCH(2)N(+)(CH(3))(C(n)H(2n+1))(CH(2))(3)Si(OCH(3))(3)]X(-) (n-X, n=10-18, X=Cl, Br, or I), were synthesized with the aim of using these agents to make material surfaces antimicrobial for a long period of time. Measurements of the minimum inhibitory concentrations (MIC) against 12 kinds o...

Quaternary Ammonium Salts of Poly(N,N-dimethylaminoethyl methacrylate) as an Efficient Antibacterial Agent for Polylactide Textiles

TOXICOLOGICAL STUDIES ON CERTAIN AMINOALKYL ETHERS AS POTENTIAL LONG-ACTING LOCAL ANAESTHETICS

The acute intravenous toxicities of a selection of three potential long-acting local anaesthetics belonging to the series of2- phenoxyethyldialkylamine were determined in mice. Two of the compounds were tertiary amines and the third a quaternary ammonium derivative.The I.V. median lethal dose, (LDso) of one of the tertiary compounds, 21A [N, N- diethyl-2- (2,6- diisopropyl) ethyl amine hyd...